Video Toaster

Audio quality is bad due to the room being boomy and the microphones on my camera being tiny. There ought to be Official Footage showing up soon that will likely sound much better.

I recommend listening to this on big speaker system with the EQ spiked for mids for maximum comprehensibility.

Post Ignite Talk

As I mentioned somewhere down below, I was selected to give an Ignite talk about informational processing in biological systems. The talk happened tonight with an audience of about 500 people, and I completely deviated from my prepared notes and winged it very successfully (the drawing together of informational threads when I improvised was better than my notes). I even convinced my brother and sister to do an interpretive dance while I talked to illustrate the transmission of information from DNA to RNA to protein, even though one of them got dropped by the other in the middle of their big 2-person cartwheel (they made up their routine).

After the presentation, a bunch of people whose names I no longer remember shook my hand and told me that I'd given a great talk that was very interesting and many people shared their stories with me of how molecular biology has randomly affected their own lives. There were also a lot of people who knew about the Central Dogma, but had always viewed it as something to be memorized and had never considered biochemical pathways to be a form of useful, active information. Nonetheless, what people very specifically pointed out about my talk were my slides. I painted about half my slides by hand with soluble ink and watercolor. Here are many of them:

Translation.


Protein Folding.


Sonic hedgehog. It helps you tell your head from your ass.


Sonic Hedgehog talking to his buddies Smoothened and Patched.


Concentration gradient of Sonic Hedgehog helps Embryonic Pony determine anterior-posterior patterning.


Transcription. I chose to leave out semi-conservative replication to keep my talk focused.


Proteins have distinct functional motifs, like this one's tongue.

Other presentations ranged from mastodon hunting technology to home funerals to spaghetti bolognese and were overall quite excellent. A program of the evening can be found here, and I will post video of the event once my brother returns my camera. I would certainly do one of these again, and have even submitted a proposal to give a TEDxUM talk in April. I'm thinking Immunology in 15min.

Consultant Toaster

I have decided to do some consulting on the side to bring in some extra dough. And by dough, yes, I do mean that I will accept payment in cookie dough, but it better not be peanut butter cookie dough or I will cut someone*. Seriously, peanut butter belongs with jelly on bread, NOT IN MY COOKIES!

Anyway, I have noticed a large number of people who complain about the greater-than-desired circumference of their waistlines very often. I cannot force these people to do sensible things such as eat better or exercise more regularly, and I am wholly unqualified to perform bariatric surgery. Therefore, I will help motivate them to exercise more intensely.


For just $20/session, Toaster will chase you full-speed with a pointy stick. You supply the pointy stick! Each time you slow down or stop fearing the stick, Toaster will give you a gentle jab with the stick to re-motivate you.

And for just $50/session, Toaster will come to your house in the morning and ambush you with not just one, but TWO pointy sticks as you walk to your car and chase you all the way to the nearest health food store, lurk ominously until you have purchased low-calorie, high-fiber foods, and then chase you back to your home screaming obscenities in a foreign language of your choosing!

Toaster is offering this service for a limited time only because he is well aware of the rate at which people lose their convictions to stick to their New Year's Resolutions. So don't delay, email Toaster now to schedule your first one-on-one personal weight-loss consulting session!!!

*Even if that means drawing a hotsauce face on a block of tofu and slashing at it.

With a What?

For the hackerspace, I send out a lot of emails. Most of them get ignored, but some of them stick. One of the ones that got a reply was a request to tour a museum collection of rare and antique musical instruments that the university's music school owns. In one of the conversations we had with the outreach director of the collection, we decided that co-hosting an educational event that melds technology and music into a workshop for kids and their parents would be an excellent idea. This is what is referred to as a Make and Take, particpants register, pay a fee for parts, come and get taught how to make stuff, and then get to take it home with them afterwards.

So, like a good engineer scientist (hacker?), I started thinking about what kinds of musical/technology projects we could conceivably build in a few hours. A while ago, Abel Pharmboy, a fellow science blogger, scientist, and musician linked me to the trailer of "It Might Get Loud" which showed Jack White of The White Stripes making a primitive electric instrument out of a 2x4 plank. This got me thinking about what sort of materials an instrument pickup could be made out of with the eventual thought of making a plank guitar. The potential for a Make and Take with the music museum gave that notion impetus, so tonight I built a 2 string electric slide guitar.

Figure 1: It's not exactly science, but it does make noise!

I used a 1"x4" plank, the voice coil of an old telephone (has lots of 42G copper wire), some nails, a set of nickelwound guitar strings, 6 screws, and a glass bottle of Nantucket Nectar juice which was quite tasty.

Humbucker construction:
A humbucker is a type of electric guitar pickup that transforms the vibrations in the strings into an electronic signal. It is an electromagnet that projects a magnetic field perpendicular to axis through which the guitar strings vibrate when plucked, which induces a current. Some commerical pickups have a separate magnet for each string, and some have 1 rectangular magnet stretching under all the strings at once. I chose the latter option, and since most commercially used hardware is ferromagnetic, I figured I could use the dry-wall screws as the core of my pickup.

I began by trying to solder the 4 screws together. Turns out that silver-core solder doesn't stick very well to cold hard metal alloys regardless of how much I'd have liked it to. So I used some 20G copper wire on hand in the hackerspace to bundle the screws together. Next I tried to solder (stubborn-ness) the bundle of screws to an improvised Dremel bit to help me wind the 42G copper wire from the telephone voice coil around my ferromagnetic core more easily. This also didn't work. I wound up making a handle out of hemostats and hanging the voice coil like a spool from my soldering helping hands and winding it by hand. I got sick of this after 2h and decided the thick belt of copper wire now girdling the screws would suffice. Finally I soldered leads to the ends of copper wire (the trailing end and the beginning end that I left sticking out) and soldered that to the leads on a 1/4" audio jack someone gave to me. When I plugged it into my amp, it made clicking buzzy sounds, but this was expected since there weren't any vibrating metal objects nearby. I tried to simulate one by banging a stainless steel bowl around near it, but this doesn't work as stainless steel is a crappy magnet and it was annoying the other people present.

The guitar:
When I embarked on this phase of the project, I immediately regretted that the hackerspace doesn't have a T-square yet so I don't know if my lines are even close to even. Nonetheless, I began by plotting out a point near one end of the plank and nailing an E and D string through their winding holes to the board with skinny nails. Then I played with the placement of the glass juice bottle as an acoustic resonator and bridge and decided that about 4.5" was good for tension. I used 4 nails to create a little cradle/fence that keeps the bottle in place while also laying it flush against the plank.

Creating functional tuners was more difficult. I found 2 wood screws and tried to tie the strings around them to no success, hoping to be able to tune the guitar with a screwdriver. None of the knots stuck, they just rotated. I had expected about as much. So I hauled out the metal cutting bit of my Dremel and deepened one of the notches on the screw's head to be flush (made lots of pretty sparks that didn't start any fires). Then I filled the screw hole with molten solder and poked the end of the string into it and held it steady until it cooled, then used needlenose pliers to bend the string down to loop around the screw. This worked well, but since I had filled the screwdriver holes with solder, I had to use the needlenose pliers to tune, but tune I eventually did, with the supposed E string winding up tuned to a D2 and the supposed D string winding up as a C3.

The humbucker is stood up near the tuning pegs by 2 small nails.

Sound:
It's quiet. At least, it's quiet when it's plugged in inasmuch as it has a very low signal to noise ratio. Acoustically, it is surprisingly loud and was causing loose screws and nails to bounce about on the table surface when laid flat. I had to run it through a pre-amp with the volume boosts, EQ boost, and gain all the way up to get an appreciable signal out of it. But once I did it was loud and gritty with a very steely twang. It is a bit awkward to play, but that's part of what makes it cool. I quickly found the sweet tonal spots on the neck of the guitar and began to bang out simple rock and roll chord processions.

The signal is loaded with tones of natural distortion, so much so that hooking up my Boss Bass Distortion pedal didn't impact the tone or intelligibility of its done much at all.

What I Would Do Differently Next Time:
1) Use an actual magnet for the pickup core.
2) Find a way to wind the copper wire around the core mechanically instead of by hand.
3) Wax the wound wire around the pickup to give it some insulation from outside interference.
4) Mill tuner screws with holes through them to thread the strings through. Find a kind-of-flattened bottle to use for the resonator to decrease the necessary height of the strings from the board so I can also make a flatter pickup.

7 Kinds of Awesome Busy

I have been 7 different kinds of awesome busy lately, although at the moment exhaustion is chipping away at the thick layer of exuberance I've been smearing across my forehead lately. Please do not expect this post to be in chronological order.

Last Tuesday the flow cytometer I needed to get data was broken. So instead I went to Chicago and Milwaukee and drove back in the same night for the Two Hands Project. I also went to Boston for a week at the beginning of the month with absolutely no hotel reservations, just friends of my brotherfriend to stay with. There I met Prime*, who is awesome in 17-8,597 different ways and I'm 97% certain that I'm in love with her now and I can't help it and don't care except that there's a rather inconveniently large physical space between us (1Mm, too big for catapults!). We're trying to figure out how to fold the space between us into technical nothingness, so if you live between Michigan and Boston please be aware that there may soon be a sudden extreme change in the topography of your region. I'm sorry, Cleveland, but Prime sends me cookies and cookies > Cleveland, although it should be noted that I can be bribed with plane tickets now.

I did many other things in Boston, some of them rather unbloggable** now that I know my boss reads this site, but they include surviving biking through downtown Boston traffic with several kgs of computing and goggles and letting complete strangers surprise-dye my hair however they wanted to. They're not strangers anymore and my hair was a very lovely bright pink for about a week when it faded to a strawberry blonde. However, the purple sides did not fade nearly so quickly and now, even after buzzing away the unruly mop that needed trimming anyway, I have a subtle bright yellow blotch on one side of my head.

Regarding blog-reading bosses, I changed laboratories shortly before going to Boston and am quite pleased with the change. In Immunolab, I read papers to actually apply them to the science I'm doing and planning instead of just reading because I'm bored, and doing so matters(!) and this is also awesome even though it has also resulted in a drastic cut in how many PLoS Computational Biology articles I have time to read. I expect to find an equilibrium again sometime as I climb the learning curve.

But as for equilibria, that's been thrown even further off balance by trying to organize a local hackerspace. And that brings me back to the Two Hands Project, but only in a moment. A hackerspace is a place where creative awesome people can come to build their ideas, talk technical shop, imagine, invent, innovate, destroy and re-create whatever they want to. It's essentially a community in a common shared working space with shared tools and parts, and maybe even eventually club-like membership to buy those parts, that fosters creative productivity by pitting like-minded people of completely different backgrounds into their own creative passions. These emerging spaces have the potential to remodel the entire American economy by shifting innovation from closed-source company driven patents to fast and flexible open-source crowdsourced invention. So far we have computer programmers, musicians, roboticists, artists, biotechnologists, cooks, textilers, and other crazily awesome people coming to meetings and generating large numbers of incredible project ideas. However, forming this group involves a lot of email management, community outreach, calender planning, part sourcing, charter writing, agenda creating, etc etc etc and I for that I am grateful that I can rely on most of my friendfamily, who're also all embroiled in this.

And yes, I have a friendfamily that has coalesced. Sister Doom, Brother Discord, Brother Deliverance, and myself, Brother Destruction. These are people whom I can completely count upon to have my back, whom I can trust and who know that they can depend upon me as needed. Sometimes I want to kick Brother Discord in the face, but that's probably because he's also my roommate. Sister Doom and I drove to Chicago and back last Friday to pick up a stranded Brother Deliverance.

But The Two Hands Project is also awesome. As I understand it, Brother Deliverance first came up with the project when he found out that JetBlue was offering a $600 ticket that lets you fly as much as you want from September 8th to October 8th. So he put out a call for donations at http://www.twohandsproject.com and raised enough money for a ticket and people donated equipment, and 2 have even joined him on his bad dash from coast to coast. It was with him and his crew that I (politely and enthusiastically) stormed Pumping Station One in Chicago, went on to interview James Carlson (director of Bucketworks in Milwaukee), and then drove from Milwaukee back to Ann Arbor so I could be back in lab by 10am. Because Brother Deliverance et al are too busy recording footage, flying, and meeting awesome people across the country to keep up the blog at Two Hands Project, they've enlisted me to do it for them remotely. I posted the first semi-polished video from San Francisco's Noisebridge and The Internet Archive*** today here and will be posting a string of profiles of hackers/makers soon.

There're some sweet experiments coming up that I am very excited about, and I just realized that I forgot the slip of paper that has the part name of the low-voltage audio amplifier I wanted to buy from RadioShack tomorrow on my desk in the lab.

I'm not quite sure what to do with Atomic Pudding. On the one hand, I could just use it like I've used this venue and let my awesome shine through, but on the other hand I liked what I was doing with open-access research and interviews, but it was just getting absolute crap page views and as such I'm not sure I was doing very well with it. Thoughts?

I also went out to visit i3 Detroit recently (Wednesday night, I think?) and had mjaddra before that (I think?) after a local maker/hackerspace meeting that Brother Deliverance recorded for the Two Hands Project (I had a lapel-mic, but was probably still unintelligible) and invited them to the free Drupal Web Development class that our as-yet-unnamed space**** is holding this coming Wednesday. And somewhere in here I know I made some really awesome live music with a fellow maker/hacker at a meeting sometime that may have been last night but I can't be certain. Wasn't I in Boston last night?

*Whose intellectual and physical hotness are mutually inclusive and inseparable properties! In testiment to her awesomeness, note that she was the first person to ever convince me of the functional utility of buying clothes that don't need to be modded to fit and has even inspired me to replace the whiskey in my burritos-cookies-and-whiskey diet with vegetables!
**Get your mind out of the gutter!
***Technically not a maker/hackerspace.
****We're working on it!

P.S. - I don't recommend prying all the keys up off your keyboard and rearranging them from QWERTY to DVORAK before you know DVORAK very well. Makes passwords very difficult.

Moving Forward List of Things to Make Done and Do

Thank you all for your kind words and support. I appreciate it. Toaster is tungsten alloy in more properties than just density. Last night I took me my sledgehammer and hewed away mightily at an undisclosed object (5th Amendment of the U.S.A. Constitution) until the following plan to keep my hands busy and mind occupied had formed.

1) Make food:

• Bake cookies. Perhaps cayenne pepper, cinnamon, Tobasco, dark chocolate cookies would be tasty. Note: first learn how to bake.
• Make and consume these.
• Cook something more than pizza and frozen burritos*.

2) Purchase soldering gun and solder stuff:

• Take apart defunct laptop, fix, and reassemble.
• Construct tiny vacuum cleaner to get cookie crumbs and charcoal shavings out of my computer keyboard.
• Build computer speakers. Not sure whether to use this or that as a chassis.

4) Read more papers.

5) Rock the fuck out:

• Begin each morning by rocking out.
• End each night by rocking out.
• Rock out in the lab.
  

6) Kick Zant and Bowsers' asses** all over the TV screen and finally beat the games.

7) Grow stuff.

• Try to grow a beard, just to see if anyone notices***.
• Grow something edible.
• Grow my hair back out of this stupid, doofy haircut I mistakenly went and got. With this, I look more like a normal scientist than a Mad Scientist, and this displeases me. To the credit of my scalp, however, it is forming multiple cowlicks despite the shortness.
• Continue growing muscles to become less scrawny. Having the approximate physique of a stick figure and the disproportionate head of an anime character has lost its novelty.

8) Get business cards.

• "Toaster Sunshine; (contact info); Lisenced Zombie Hunter; Professional Mad Scientist."
• Resist urge to get "Pardon me, sir/ma'am (circle one), I couldn't help but notice you're a douchebag" cards and hand them out as needed.
  

9) Be more social.

• Force myself out of my lair and interact with humans in their natural habitats.
• Leave phrenology calipers at home as these will probably not endear me to anyone.
• Don't talk about Mad Science when first meeting someone to avoid scaring them away.
• Suppress Mad Scientist Laugh in public.
• Do not wear top hat to happy hour, as this might be construed as rude.
• Quantify human body language. May need calipers for this.
• Drink more? My liver has gotten pathetically complacent.

10) Finish out cartoon commissions.

11) Gather data around hypothesis that "charm" is just "normal social graces" integrated over a power law with range 5 to infinity (Blogger interprets proper mathematical notation as an in-line html style tag).

*The 4 Food Groups of Toaster: frozen burritos, sushi, cookies, and orange juice.
**For non-nerds, that corresponds to Legend of Zelda: Twilight Princess and Super Mario Galaxy, respectively.
***Last time Toaster tried to grow facial hair no one noticed for weeks, likely because it is blond and therefore only visible in limited lighting contexts.

Also: COOKIE PORN!!!