I was speaking today with a "colleague" of mine about self-experimentation, and she at one point in the conversation she remarked that she thought that "Why the hell are we becoming scientists? I mean, you and I, we are the worst people to be scientists!".
I took umbrage. Lots of umbrage. True, that I sometimes wonder what the nutritional value of my reagents are, or what it feels like for a gastrointestinal epithelial cell to be colonized aggressively by an invading and effacing pathogen. And all she did is blather on about vanillin stains smelling good.
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