02 December, 2009

Cookie Reviews: Erin Baker's Breakfast Cookie

It is a well established fact that Toaster likes cookies quite a bit. You may even go so far as to be able to call him a connoisseur and you'd not be inaccurate. To better guide your cookie eating through his own experience, Toaster offers the following cookie review:

The other day I had missed the bus and I was hungry, so I walked over the the nearby drive-through coffee house looking for quarters and saw that they had a sign for "breakfast cookies". Now, I eat cookies for breakfast sometimes anyways, so this was nothing novel, but the official legitimization thereof was. As the baked goods that this coffee house sells are normally excellent, I figured I'd give it a shot.

I was presented with a pre-packaged choice of Erin Baker's Peanut Butter, Oatmeal Double Chocolate, or Oatmeal Raisin Breakfast Cookie. Normally I'd go with an oatmeal raisin cookie over most anything else any day, but figured today I'd go for the double chocolate as I'd only slept 2h the night before and could use the extra sugar and chocolate-borne theobromines as stimulants.

It turns out that Erin Baker's Breakfast Cookies are edible.

The cookie itself was moist, chewy, and firm, almost everything a cookie should be (also needs crumbly), but it managed to get their respective parameters mixed up. It was too moist, too firm, and too chewy. There was no crunch to this cookie whatsoever, not even a hint of that perfect outer crustiness that I seek. It was also very dense. I had expected unusual density because it billed itself as a breakfast cookie meal replacement, but this was pumpernickel in the realm of baguettes. Furthermore, despite this being a Double Chocolate cookie, it still managed to taste like peanut butter and the chocolate chips tasted like soy carob despite the ingredients claiming real chocolate.

Examining the packaging more closely, it turns out that this was the dreaded oxymoron Healthy Cookie. No butter in it at all. Just a lot of molasses, special organic wheats, and weird juice extracts instead of sugar. Now, I can understand using raw cane juice or unrefined sugar in a cookie, but relying solely on cane sap and pear extract as sweetener is contrary to the spirit of cookiedom. And it had fiber. Lots of fiber. Toaster is fine with lots of fiber as most everything that is not a cookie, burrito, Tabasco, or whiskey that he consumes is vegetable or whole wheat, but this was like having an ingot of sawdust sitting in my belly for a few hours.

Erin Baker's Breakfast Cookie:
Texture - D
Taste - C
Idea - B+
Cookieness - D

Note - I am going to review other cookies in the future, and I will strive to only do so with brands available in most of the United States or, if homemade, only when I am also able to post the recipe.

30 November, 2009

Power Tools

Just when I begin to believe that maybe I am wise enough to use power tools.

28 November, 2009

Cloudy With a Chance of Meatballs

I make no secret of the fact that I still really like cartoons and comic books. Entertainment material written for children is frequently far more interesting, imaginative, and deep than the endlessly recycled fodder that keeps getting repackaged for grown-ups to consume. So I continue to watch them. In fact, the last time I went on a date-like date I went with Prime to see "Shorts" in Boston.

Anyway, last night I watched "Cloudy With a Chance of Meatballs" long-distance with Prime, and the movie almost got it. I am all for kids' movies that hype the coolness of science, such as "Meet the Robinsons" or "Dexter's Lab" and Cloudy tried really hard to do so. It accomplished the hype, but unfortunately it did so so well that it completely rolled right over a potentially great sub-story that could have brought the science hype to a perfect boil. In the movie, Flint is the errant mad scientist son trying to save his sardine town and inadvertantly makes food weather while Sandy is the weather channel intern who gets sent to the island right as the weird food weather starts happening. It turns out that Sandy, who was sent for being so very perky and nice, was actually a meteorology nerd growing up and that she chose to stop wearing her glasses and let her hair down to become socially accepted. Flint puts her glasses back on and likes her as a fellow hot science nerd, but then makes the mistake of ignoring the warnings of her science when his own mad science begins to roll out of control, thereby stunting her nerd-ful self-actualization. And even though Sandy goes on to help save the day with Flint, she still winds up in a backseat role and is never redeemed by her science in the face of those who made fun of her.

The film could have been a much more positive role for all young people seeing science if it had not just shown science as the province of a crazy dude and rather shown the benefit of including the female nerd's scientific expertise as equally valuable. That being said, Flint's habit of narrating his actions ("Planning! Welding! Wiring!") was pretty awesome, and it does not detract from my urge to wear a full-length cape at the lab bench sometimes.

26 November, 2009

Peritonsillar Abcess

On Monday night, while I was showering I began to feel dizzy and nauseous, so I reached for the wall of the tub to steady myself and instead abruptly found myself face-first on the floor outside the tub with no recollection of falling. So I picked myself up from my elbows and forehead and tried to figure out why I still had the shower in my hand. Logically the best thing to do was to get out of the shower and lie down somewhere with more padding as I was still rather dizzy and was entirely unsure of where my feet were. So I rinsed off the suds, turned the water off, reached for my towel, and promptly found the floor on the other side of it. Somehow this got me angry enough to stop feeling dizzy and I managed to make it into my room to dry off and put on pajamas. I set my alarm to wake me up in 1.5h and kept doing so throughout the night as a concussion watch. It didn't feel like a concussion so much as a bruise, but I wasn't going to take any chances.

Ordinarily, this kind of thing would prompt one to go see a doctor the next day. Not so much for me. I had lost my voice and was having great difficulty swallowing food and liquids 1.5d before, so I figured by that point that I was rather dehydrated and as such the hot shower steam simply got to me. No, it took another night where I couldn't tell the fever sweats from the drool and not even being able to comfortably drink water around the bellicose pin cushion that had taken up residence at the back of my throat to get me to seek medical attention.

By this point I could barely even manage a hoarse whisper, so after I'd managed to phone in an appointment at the student/staff clinic that afternoon I tried to legibly write down the timecourse that symptoms had emerged on. It helped. The doctor at the clinic looked into my throat and saw the same thing I had for the past few days, the right side of my throat swollen so much that my tonsils were stuck to it. I had attributed it to weird strep throat and expected it to start improving any time, maybe I'd leave with cyclosporin antibiotics and an analgesic gargle. She recognized it as a peritonsillar abcess, which is basically a very acute infection in a very limited site that gets massive neutrophilic infiltration and subsequent inflammation (pain and pus) and that if it was left untreated it could wind up occluding my trachea. So I was sent off to the ER at the university's hospital, trying to figure out how they were going to drain an abcess at the back of my throat.

I've had an abcess before. I developed a topical abcess on my chest one season where I was playing cello for Bach's "Double Violin Concerto in D Minor - Vivace" and practiced so much that the contact point for the cello on my chest developed into an abcess. But they're easy to deal with on the skin surface, even if it did open back up after draining right as I arrived at my stats class.

I arrived at the ER and was fairly quickly seen, and within about 1.5h they determined that I could have IV fluids, a dose of antiinflammatories, a round of cyclosporins, and morphine. They pushed all of these at once and the nurse wrapped me in warm blankets and suddenly I was a sublime cloud. The clot of burrs at the back of my throat was gone, and I was simply at absolute peace in a way that I have not been since last I saw Prime. I sat somewhere between wakefulness and dozing and I have no idea how much time passed in this state.

Then a resident walked me (I denied the use of a wheelchair because I wanted to see what it would be like to try to walk on morphine [not easy]) up to the otolaryngology clinic and sat me in a procedures room. A nurse bustled about and laid out far more surgical instruments than could possibly, POSSIBLY, be used at once, right? Once I realized that there was absolutely no way topographically that all of those pointy and sharp objects could be applied to the back of my throat simultaneously, I was greatly reassured.

Eventually, one doctor did the procedure and I got to help. First he sprayed the back of my throat with Lidocaine, which does not taste good but thankfully numbs that which tastes and followed it up with an injection of Lidocaine into the abcess. Next came a 10ml evacuation syringe, which drew out about 7ml of pus. Then there was a tiny little scalpel blade to widen the incision and another evacuation of a similar volume, and then I sat there dutifully holding the suction hose drawing away the remaining blood and pus into a bucket on the wall (no appreciable further volume). I'm now on a course of major cyclosporin antibiotics (more than 1.0g/d!), a course of antiinflammatory steroids, and some painkillers, and there will be a follow-up appointment to make sure the abcess hasn't reconsolidated and needs further drainage. It was also mentioned that there is a risk for repetitive abcesses here now and that I should consider getting my tonsils out to stop them from happening. On the last point, I'm not yet sure.

Abcess pus. Pic taken while doctor wasn't looking. I could make several inappropriate and disgusting Thanksgiving food references here, but I shall refrain for your sake.

UPDATE: Culture of above pus showed that the cause of the peritonsillar abcess was clindamycin-sensitive Fusobacterium necrophorum, which is apparently a normal microbial resident of the mouth (no satisfactory reference found for this yet save one that cites isolation of it from canker sores), but apparently it causes a hoof disease in sheep called scald and it survives in the soil of sheep pastures for years.

21 November, 2009

With a What?

For the hackerspace, I send out a lot of emails. Most of them get ignored, but some of them stick. One of the ones that got a reply was a request to tour a museum collection of rare and antique musical instruments that the university's music school owns. In one of the conversations we had with the outreach director of the collection, we decided that co-hosting an educational event that melds technology and music into a workshop for kids and their parents would be an excellent idea. This is what is referred to as a Make and Take, particpants register, pay a fee for parts, come and get taught how to make stuff, and then get to take it home with them afterwards.

So, like a good engineer scientist (hacker?), I started thinking about what kinds of musical/technology projects we could conceivably build in a few hours. A while ago, Abel Pharmboy, a fellow science blogger, scientist, and musician linked me to the trailer of "It Might Get Loud" which showed Jack White of The White Stripes making a primitive electric instrument out of a 2x4 plank. This got me thinking about what sort of materials an instrument pickup could be made out of with the eventual thought of making a plank guitar. The potential for a Make and Take with the music museum gave that notion impetus, so tonight I built a 2 string electric slide guitar.

Figure 1: It's not exactly science, but it does make noise!

I used a 1"x4" plank, the voice coil of an old telephone (has lots of 42G copper wire), some nails, a set of nickelwound guitar strings, 6 screws, and a glass bottle of Nantucket Nectar juice which was quite tasty.

Humbucker construction:
A humbucker is a type of electric guitar pickup that transforms the vibrations in the strings into an electronic signal. It is an electromagnet that projects a magnetic field perpendicular to axis through which the guitar strings vibrate when plucked, which induces a current. Some commerical pickups have a separate magnet for each string, and some have 1 rectangular magnet stretching under all the strings at once. I chose the latter option, and since most commercially used hardware is ferromagnetic, I figured I could use the dry-wall screws as the core of my pickup.

I began by trying to solder the 4 screws together. Turns out that silver-core solder doesn't stick very well to cold hard metal alloys regardless of how much I'd have liked it to. So I used some 20G copper wire on hand in the hackerspace to bundle the screws together. Next I tried to solder (stubborn-ness) the bundle of screws to an improvised Dremel bit to help me wind the 42G copper wire from the telephone voice coil around my ferromagnetic core more easily. This also didn't work. I wound up making a handle out of hemostats and hanging the voice coil like a spool from my soldering helping hands and winding it by hand. I got sick of this after 2h and decided the thick belt of copper wire now girdling the screws would suffice. Finally I soldered leads to the ends of copper wire (the trailing end and the beginning end that I left sticking out) and soldered that to the leads on a 1/4" audio jack someone gave to me. When I plugged it into my amp, it made clicking buzzy sounds, but this was expected since there weren't any vibrating metal objects nearby. I tried to simulate one by banging a stainless steel bowl around near it, but this doesn't work as stainless steel is a crappy magnet and it was annoying the other people present.

The guitar:
When I embarked on this phase of the project, I immediately regretted that the hackerspace doesn't have a T-square yet so I don't know if my lines are even close to even. Nonetheless, I began by plotting out a point near one end of the plank and nailing an E and D string through their winding holes to the board with skinny nails. Then I played with the placement of the glass juice bottle as an acoustic resonator and bridge and decided that about 4.5" was good for tension. I used 4 nails to create a little cradle/fence that keeps the bottle in place while also laying it flush against the plank.

Creating functional tuners was more difficult. I found 2 wood screws and tried to tie the strings around them to no success, hoping to be able to tune the guitar with a screwdriver. None of the knots stuck, they just rotated. I had expected about as much. So I hauled out the metal cutting bit of my Dremel and deepened one of the notches on the screw's head to be flush (made lots of pretty sparks that didn't start any fires). Then I filled the screw hole with molten solder and poked the end of the string into it and held it steady until it cooled, then used needlenose pliers to bend the string down to loop around the screw. This worked well, but since I had filled the screwdriver holes with solder, I had to use the needlenose pliers to tune, but tune I eventually did, with the supposed E string winding up tuned to a D2 and the supposed D string winding up as a C3.

The humbucker is stood up near the tuning pegs by 2 small nails.

Sound:
It's quiet. At least, it's quiet when it's plugged in inasmuch as it has a very low signal to noise ratio. Acoustically, it is surprisingly loud and was causing loose screws and nails to bounce about on the table surface when laid flat. I had to run it through a pre-amp with the volume boosts, EQ boost, and gain all the way up to get an appreciable signal out of it. But once I did it was loud and gritty with a very steely twang. It is a bit awkward to play, but that's part of what makes it cool. I quickly found the sweet tonal spots on the neck of the guitar and began to bang out simple rock and roll chord processions.

The signal is loaded with tones of natural distortion, so much so that hooking up my Boss Bass Distortion pedal didn't impact the tone or intelligibility of its done much at all.

What I Would Do Differently Next Time:
1) Use an actual magnet for the pickup core.
2) Find a way to wind the copper wire around the core mechanically instead of by hand.
3) Wax the wound wire around the pickup to give it some insulation from outside interference.
4) Mill tuner screws with holes through them to thread the strings through. Find a kind-of-flattened bottle to use for the resonator to decrease the necessary height of the strings from the board so I can also make a flatter pickup.

18 November, 2009

Toaster the Psychic Organ Builder

So the other day I was standing inside of a 4-story pneumatic pipe organ while it was being played thinking to myself: "Holy crap I'm inside of a 4-story pneumatic pipe organ while it is being played!" when it occurred to me that maybe I might actually know something. For a while I've been feeling like I have spent so much time and effort learning about molecular biology that I no longer know anything actually useful outside of the laboratory. This feeling was jade creeping into the awesomeness of science, and I found it best to promptly shake it off like a dog after a bath and go roll around on the floor joyously with all my legs in the air. I mean, sure this science sometimes appears to be nothing more than moving tiny amounts of expensive liquids around while muttering vague incantations about hypotheses and replicability. But what it is, what molecular biology fundamental is, is me dissecting LIFE ITSELF with my MIND!!! I could have all the fancy tools an R01 can buy at my disposal and a hammock above my bench, but those things wouldn't mean crap for meaningful, insightful science if I didn't start by designing an elegant, productive experiment. It's like I'm telekinetic at the molecular level, because I have to imagine the true nature of all these stochastically interacting proteins, genetic elements, or other molecules and their aggregate behavior clearly, I have to fix it in my mind and strip away the limitations of my vision to harness the quiet power of chemical reactions and hydrogen dipoles to prove the accuracy or folly of what I have captured with my mind.

Sure, this science doesn't have the immediate satisfaction of swinging a hammer and building a chair, the delay to sate the fundamental human need to create and explore burns on a longer fuse, but oh, when it connects it is all the more beautiful. I may not be building a pipe organ, but I am reverse-engineering something many more times intricate when I can't even see it with my naked eyes. That. Is. Awesome.

15 November, 2009

We Need a Verb!

You know that thing that sometimes crazy people, or parents, do where they put their mouth on another's belly and then exhale forcibly, making a very loud and ticklish THWBBT!!! noise?

Why doesn't the English language have a verb for that, or at least a name!? Really, it'd only be decent and all...

04 November, 2009

On Recognizance of Competence

Recently I had some business cards with my personal contact information printed up to help me network more effectively and remain in touch with the awesome people involved in science and technology that I've been meeting. As these aren't for work, per se, they have a picture of a Velociraptor skeleton, a quote from Mark Twain ("The more you explain it the more I don't understand it." A good reminder to keep things simple and short, I think), and "Awesome Scientist #17" as my job title, even though it doesn't signify exactly where I work. I'm not sure exactly who the other 16 are. About this time, I realized something: people think I'm smart. This is strange.

I don't know that I'm smart. I don't feel any differently and I cannot imagine being any other way. Frankly, most of the time I feel stupid because there is so much that I do not know and that which I have captured in my mind is so insignificant compared to how much awesome there is to learn. I only know that I am smart by interacting with other people and seeing the reflection thereof. I used to be more reclusive and introverted, counting bacteria by day (doing science) and making music alone at night, but now I have been forcing myself out of that bubble and taking on challenges and actually talking to real people*, doing SCIENCE in the new lab job, and dropping awesomeness and scientific knowledge through the informal molecular biology classes I've been teaching in the Makerspace (Youtube soon). Through all of this, I have come to realize that people actually value my knowledge, experience, perspective, and opinion. I have more opinions than anything else, but it's still a bit strange because I still feel as though I haven't done anything truly awesome that deserves any respect yet.

I probably never will. I realize this, because I know that my ambitions and analytical nature will never let me rest because there will always be more science and/or awesome always going up or something else shiny will captivate my interest. The positive side of this, I think (self-delude?) is that it'll keep me busy, and that's a very good thing as a bored Toaster digs out his backpack of tools and starts taking things apart. The other positive of this is that by taking on more, I hold myself to doing more and am forced to learn how to synthesize all the enzymes to help masticate all that I've bitten off. I used to read scientific papers for fun, but now my boss sends me papers faster than I can read them. I used to make music just for my own enjoyment, but after doing in impromptu live set I have been volunteered to make live music at an art show in 10 days (and all I have prepped are 2 remixes of the Leekspin song). I used to tinker using just my own limited tools and experience, but now that I've helped create a cooperative makerspace I have access to a much wider range of tinkerables and tools (I even coined a new term last week; making a silly, simple mistake now has the swear word: "BLOOTLELOOT!" attached to it after I mistook a diode for a resistor and soldered it to an LED). I used to play with data for weeks just out of curiosity, long after the main aim of the experiment had been answered, just to see what I could draw out of it, but now I have so many data sets to mine that pure play has transmuted into teasing the data for the prettiest results.

These are good changes. It was silly of me to ever think I should first know what I was doing before trying. This is much more informative.

*Not that bloggers aren't real people, but Internet-based communication is easier because it has a backspace key.

27 October, 2009

Language Blathering

I posit that language acquisition is driven less by intellectualism than daily utility. A recent post over at Greg Laden's Blog got me to wondering why Anglophones remain so stubbornly monolingual when so much of the world speaks a couple different languages fluently. Upon ponderation, I believe that Anglophones don't learn second or third languages because we don't need to, not really anyway. This isn't to say that this attitude is right, nor that I condone it, but from England on outward to the United States of America to Austrailia, English-speakers have been very successful at ensconcing themselves in geographical isolation, cultural imperialism, and economic massiveness underwritten by strategic military stubbornness. These three conditions having combined to make English the predominant formal language in the world despite its sillinesses.

We dumb Americans don't learn French, Spanish, Hindi, or other non-English languages because we have no daily use for them. We may take a few semesters of a foreign European language in high school, but because we don't have a need to use them, nor a community, space, or occasion to trot them out, we largely forget them. And when we go to other countries we have the privilege borne out of economic massiveness that leads us to expect, and even demand, that our hosts speak our language even as we remain entirely ignorant of theirs.

This isn't necessarily a good thing, but maybe this is why it is the way it is.

For the record, I speak and read German fluently enough to also make out written Dutch and Swedish and can stammer out just enough Spanish to keep myself fed and housed. I intend to learn French if I ever find time because I think it sounds funny, and Mandarin if I can.

18 October, 2009

Marathon Science

My boss told me that I should factor in that everything will take much longer when I have many samples and that I should plan my time accordingly.

She was very right.

In fact, she was so correct that I wound up pulling 29h in the lab, and 14h the day before, to get Experiment done. There weren't that many samples to begin with, but by the time that I split those samples into cell culture under different conditions and then stained each of those conditions for different sets, I had a couple hundred samples to run on my hands (or, rather, in a tray because I couldn't carry them all at once).

What I found most interesting about this (aside from the Science of it that I can't blog yet), was how all-night science affected me. The entire night was an odd rollercoaster of exuberancy and despondency.

11a - Got to lab, felt guilty about being late but vindicated by 14h there yesterday.
12p - Relieved to see that samples had not drowned in melting ice bath overnight, put into refrigerator to finish staining later because Machine was scheduled out into early evening.
1p - Indian food buffet!
2p - Talk to visiting scientist, then journal club.
3p - Journal club.
4p - Realized that I didn't have enough Enzyme, so I went to go get more from our super-convenient on-site Enzyme Store.
5p - Started finishing staining.
8p - Finished finishing staining, Machine time.
10p - Done with Machine for now.
11p - Pulling cell culture.
12p - Plating for staining, blocking, singing deliberately off-key.
1a - Sandwich and caffeine time.
2a - Primary stains, dancing around laboratory to punk music.
3a - Washes. Laboratory is very cold. Sweater not helping. Note that this parallels drop in body temperature that occurs when sleeping. Turn up lab thermostat just a little bit. At least it's warmer in the cell culture room.
4a - Fixation. I could have gone home and slept at this point, but didn't want to have to come back in later. Arikia and I discuss what we carry around in our backpacks/bags, she rightly points out that the contents of mine would have me on a terror watch list in no time flat. I have my laptop, a zombie comic book anthology, lots of heavily annotated biology papers, a screw driver with a full tip set (even hex wrenches!), a digital multimeter, wire strippers, a soldering gun, needle-nose pliers, gloves, fisticuffs, a gigantic rubber band, a set of Exacto knife scalpels, some faded index cards, cufflinks, a bunch of batteries, and Pepto Bismol. I do not know how old that Pepto Bismol is. Might need to add a crowbar.
5a - My pellets have disappeared. I have become paranoid and cynically convinced that all I'm doing is spending lots of time moving small bits of liquid around even though I know from doing this before that fixation can cause a change in their color.
6a - I found enough change in my pockets for a vending machine Snickers bar. It's dawn and I am shivering even with my sweater on.
7a - Still washing and enzyming, other people start to filter back in (this is Saturday now, right?).
8a - More washes and a brief 30min nap on the couch in the departmental library, which is surprisingly comfortable. Glad my phone can be used as an alarm clock, also glad that protocol has 40min incubation periods.
9a - Still can't see any pellets. Morose about prospects for data. Still washing.
10a - Final stain!!! Just one more wash...the sound that the suction makes when washing no longer amuses me...
11a - Machine time! Crap, gotta restart the machine. Fairly certain that I dozed off waiting for the machine to start up all its pumps and stuff, woke back up when I started to fall out of chair.
12p - Staining controls calibrated.
1p - Running samples, strangely extremely alert, become completely attuned to Machine such that I am already fixing a problem before it pops up a problem-prompt.
4p - Finished running samples, Machine no longer talking to me.
4.5p - Promptly miss only bus home for next hour, decide to walk instead.
5p - I am lost. I know by dead reckoning exactly where my apartment is, but there are all these inconvenient streets and houses in the way.
5.5p - Home.

Truth be told, I still didn't go to sleep until 1a. First I ate a lot of food, drank a lot of drink, and played with the new power tool that finally came in the mail even though I didn't have anything on hand that expressly needed it. I need to find space in my backpack to add this tool. And to top it all off, I even had trouble falling asleep.

UPDATE - Dremel is now in my backpack. Also found bag of 15 2" 30-Ohm speakers in there.